set and setting
Psychedelic-Assisted Therapy for Addiction
The use of psychedelic substances for treating addiction is simultaneously one of the oldest therapeutic practices in human history and one of the most promising frontiers of modern psychiatry. Indigenous cultures have used ayahuasca, peyote, iboga, and psilocybin mushrooms for healing addiction...
Ego Dissolution The Three Brain Pathways
If you look across human history, you find these incredible stories of, well, self-transcendence.
The Most Important Research You Have Never Heard Of: Grof's Psychedelic Investigations
In November 1956, a young psychiatric resident at Charles University in Prague volunteered for an experiment that would redirect the course of his life and, arguably, the trajectory of Western psychiatry. The Sandoz pharmaceutical company in Basel, Switzerland -- the same company where Albert...
Western Science Meets Indigenous Wisdom
Okay, let's unpack this. We are diving deep today into one of the most intellectually
Psychedelic-Assisted End-of-Life Care: Psilocybin, Mystical Experience, and the Dissolution of Death Anxiety
In 2016, two landmark studies — one from Johns Hopkins University, one from New York University — reported results that would have seemed impossible a decade earlier: a single dose of psilocybin, administered in a controlled clinical setting with psychological support, produced rapid,...
The Eleusinian Mysteries: How Western Civilization May Have Been Founded on Psychedelic Initiation
For nearly two thousand years — from approximately 1500 BCE to 392 CE — the most important religious ceremony in the ancient Western world took place every September at a small town called Eleusis, thirteen miles northwest of Athens. The Eleusinian Mysteries, as they were called, initiated an...
Peyote and the Native American Church: The Most Successful Integration of Psychedelic Sacrament Into Modern Society
In the Chihuahuan Desert of northern Mexico and southern Texas, a small, spineless cactus grows close to the ground. It looks unremarkable — a blue-green button, rarely more than a few centimeters in diameter, barely protruding from the rocky soil.
The Vision Quest and Fasting Across Traditions: Why Every Spiritual Culture Uses Hunger as a Consciousness Amplifier
There is a practice that appears in virtually every spiritual tradition on Earth, across every continent, in every historical period, in cultures that had no contact with one another. The practice is this: go to a remote place, stop eating, and wait.
Indigenous Psychedelic Wisdom and Reciprocity: The Ethics of Plant Medicine
The psychedelic renaissance has a shadow that its brightest advocates often fail to acknowledge: virtually every psychedelic compound that Western science is now studying, patenting, and commercializing was discovered, developed, and held sacred by indigenous peoples for centuries to millennia...
Psychedelic Integration and Ethics
The psychedelic experience itself — however profound, healing, or transformative — is only the beginning. Integration is the process by which the insights, emotions, bodily sensations, and shifts in perspective catalyzed during a psychedelic session are woven into the fabric of daily life,...
REBUS and the Entropic Brain: How Psychedelics Rewrite Reality
In 2019, Robin Carhart-Harris and Karl Friston published what has become the most influential theoretical paper in psychedelic science: "REBUS and the Anarchic Brain: Toward a Unified Model of the Brain Action of Psychedelics" in Pharmacological Reviews. The paper synthesizes two frameworks —...
Set, Setting, and Psychedelic Safety
The maxim that the psychedelic experience is shaped by "set and setting" — the mindset of the individual and the environment in which the substance is consumed — is perhaps the single most important practical principle in psychedelic science and practice. First articulated by Timothy Leary,...
Modern Sacred Spaces: Designing Environments That Elevate Consciousness
Every culture in human history built spaces specifically designed to alter consciousness. The pyramid, the cathedral, the temple, the kiva, the longhouse, the sweat lodge — these are not merely buildings where spiritual practices happen to take place.
Binaural Beats and Brainwave Entrainment: The Phantom Frequency Inside Your Head
In 1839, Prussian physicist Heinrich Wilhelm Dove discovered something peculiar. When he presented a tone of 400 Hz to one ear and a tone of 410 Hz to the other ear (through separate tuning forks), the listener perceived a third tone — a rhythmic pulsation at 10 Hz, the difference between the...