Valter Longo
Cancer: Supportive and Integrative Care
Cancer remains the second leading cause of death globally, responsible for approximately 10 million deaths annually. While conventional oncology — surgery, chemotherapy, radiation, immunotherapy, and targeted therapies — has achieved remarkable advances in certain cancer types, the overall war...
Autophagy and Consciousness: How Fasting Triggers the Brain's Cellular Cleanup System
In 2016, the Nobel Prize in Physiology or Medicine was awarded to Yoshinori Ohsumi, a Japanese cell biologist at the Tokyo Institute of Technology, for his discoveries of the mechanisms of autophagy. The word "autophagy" comes from the Greek auto (self) and phagein (to eat) — self-eating.
The Fasting-Mimicking Diet: Valter Longo's Innovation for Getting Fasting Benefits Without Fully Fasting
Valter Longo has spent the better part of three decades studying the biology of fasting at the Longevity Institute of the University of Southern California. His research has produced some of the most significant findings in the field: the discovery that extended fasting triggers stem cell...
Extended Water Fasting: The Progression From Hunger to Clarity to Transformation
Intermittent fasting is a daily practice. Extended water fasting is an expedition.
Therapeutic Fasting and Time-Restricted Eating: The Medicine of Not Eating
In a world obsessed with what to eat, the question of when to eat — and when not to eat — may be equally transformative. Therapeutic fasting and time-restricted eating (TRE) represent some of the most ancient and most scientifically validated health interventions, bridging the gap between...
Integrative Oncology: Functional Medicine Meets Cancer Care
For nearly a century, we have treated cancer primarily as a genetic disease — mutations accumulate, cells go rogue, we poison or cut them out. But there is an older thread, stretching back to Otto Warburg's 1924 observation that cancer cells ferment glucose even in the presence of oxygen — the...
Fasting Protocols: From Time-Restricted Eating to Extended Fasts
All fasting is not equal. A 12-hour overnight fast and a 5-day water fast activate fundamentally different metabolic pathways at different magnitudes.
Senolytics, NAD+, and the New Science of Longevity
Inside your body right now, there are cells that have stopped dividing but refuse to die. They sit in your tissues — fat, skin, joints, lungs, blood vessels — secreting a toxic cocktail of inflammatory molecules, tissue-degrading enzymes, and growth factors that corrupt their neighbors.
Autophagy: The Cell's Garbage Collection System and the Clarity of Consciousness
In 2016, Yoshinori Ohsumi, a Japanese cell biologist at the Tokyo Institute of Technology, won the Nobel Prize in Physiology or Medicine for discovering the mechanisms of autophagy — the process by which cells digest and recycle their own damaged components. It was a Nobel Prize for...
Caloric Restriction: The Most Ancient Longevity Mechanism and Its Consciousness Connection
Long before rapamycin was extracted from Easter Island soil, long before NAD+ was identified as a coenzyme, long before anyone knew what a telomere was, one intervention had already been shown to extend lifespan more consistently than any other: eating less.
Rapamycin and mTOR: The Master Switch Between Growth and Longevity
In 1964, a Canadian medical expedition collected soil samples from Rapa Nui — Easter Island — hoping to find new antibiotics. What they found instead was a molecule that would become the most important drug in longevity research.
Daily Spiritual Practice: A Framework for Living in Ceremony
There is a moment each morning — before the emails, before the news, before the world rushes in with its demands — when you are closest to the person you are becoming. A daily spiritual practice claims that moment.